Salivary lactate dehydrogenase in oral and potential malignant disorders

Study findings suggest a number of uses for visual aid support of Thickness Indicator Model tubes

In her first Dental Elf blog Iris Vaid looks at a review of salivary lactate dehydrogenase (LDH) as a potential diagnostic marker for oral cancer and oral potentially malignant disorders.

[read the full story...]

Diagnostic accuracy of salvia tests for SARS-CoV-2

2865674738_d577a64385_o

This review of the use and diagnostic accuracy of saliva tests for the detection of SARS-CoV-2 included 16 studies. THe findings suggests good diagnostic accuracy but furteher research is needed to determine confounding factors such as method and time of sample collection, transport medium, storage etc. prior to population testing.

[read the full story...]

MicroRNAs for diagnosis of squamous cell carcinoma

Examples_of_microRNA_stem-loops

Manas Dave looks at a review of the diagnostic accuracy of blood and salivary microRNAs (miRNAs) in discriminating oral squamous cell carcinoma. The review included 20 cross-sectional studies and suggested moderate diagnostic accuracy and higlights a potential are for larger scale studies.

[read the full story...]

COVID-19 Dental Elf Blogs – 5

coronavirus 2 (SARS- CoV-2)

Since the emergence of the SARS-CoV-2 virus just over a year ago we have published a number of dental blogs relevant to COVID-19. The blogs cover topics such as dental teams’ generic risk of disease, baseline risk of covid-19, asymptomatic patients and the risk of community spread, digital thermometers, mouthwash use, surgical mask types, gown [read the full story…]

Detecting SARS-CoV-2 in Saliva

fusion-medical-animation-EAgGqOiDDMg-unsplash

This review of the use of as a sample for the detection of SARS-COV-2 included 22 studies ( 2 case reports, 17 case series and 3 mass screenings) while SARS-CoV-2 is detected in saliva additional high quality studies are needed to determine efficacy.

[read the full story...]

COVID-19 Dental Elf Blogs -4

fusion-medical-animation-rnr8D3FNUNY-unsplash

This blog pulls together a number of our blogs on COVID-19 publishing since July. We also include links to our other COVID-19 relevant blogs published since March 2020.

[read the full story...]

Saliva in the diagnosis of COVID-19

national-cancer-institute-2fyeLhUeYpg-unsplash

Saliva has been suggested as having potential diagnostic value in COVID-19 patients. In this blog Manas Dave looks at a recent review of the subject which included 28 studies.

[read the full story...]

Avulsed teeth: Storage media used before replantation

shutterstock_70287046 - avulsed tooth

This review of the effectiveness of any technique available to laypeople for storing an avulsed tooth compared with storage in milk or saliva included 33 studies. Findings suggest that milk, Hank’s balanced salt solution, propolis, oral rehydration salts, rice water, and cling film extend periodontal ligament cell viability before replantation.

[read the full story...]

Candida albicans: higher prevalence in children with early childhood caries

shutterstock_90529192

This review of a possible association between oral Candida albicans and early childhood caries (ECC) included 15 cross-sectional studies.The prevalence of C. albicans in children with ECC was found to be significantly higher than in caries-free children.

[read the full story...]

Salivary biomarkers for diagnosing periodontal disease

shutterstock_138231533

This review of salivary biomarkers for diagnosing periodontal disease only identified 4 studies at high risk of bias but suggests a small number of potential biomarkers. However the findings should be interpreted with caution.

[read the full story...]