Significant blood loss can occur during orthognathic surgery and there are risks associated with blood transfusion so minimizing blood loss during surgery is important. A large number of trials and reviews have shown that the antifibrinolytic agent tranexamic acid ( a synthetic amino acid lysine analog ) can effectively reduce [read the full story...]
Conservation of blood is important in all forms of surgery and approximately 30% of patietns undergoing bimaxillary osteotomies require a transfusion. The aim of this trial was to assess the effect of tranexamic acid on blood loss, quality of surgical field and duration of surgery compared to the effect of [read the full story...]
Choi in a trial in 2009 found that an intravenous bolus administration of tranexamic acid at 20 mg/kg reduces blood loss compared with placebo during bimaxillary osteotomy. The aim of this trial was to test whether the use of tranexamic acid in an irrigant fluid would decrease blood loss during [read the full story...]
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