Recurrent aphthous stomatitis – topical medications

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This review of different topical medications for the management of recurrent aphthous stomatitis (RAS) included 43 RCTs. No significant differences were found for any if the treatments assessed and a majority of the included RCTs (76%) were considered to be at high risk of bias.

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Top Dental Elf blogs Oct – Dec 2022

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Our most read blogd in October, November and December 2022 covered treatments for burning mouth syndrome, recurrent oral aphthous stomatitis and preformed metal crowns on primary molars

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Recurrent aphthous stomatitis – topical interventions

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This review of the efficacy and safety of topical interventions used for recurrent aphthous stomatitis included 72 studies assessing 29 different interventions. Most of the interventions did not demonstrate significant differences with limitednumbers of studies for some interventions and overal limitations in the quality of the evidence.

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Nicotine replacement therapy – oral side effects

For inpatients with psychiatric symptoms of moderate severity, the study suggests those using nicotine inhalers were most successful overall in their quit attempts. There were no severe adverse reactions to the NRTs.

This review of the evidence on possible association between locally delivered nicotine replacement therapy(NRT) and oral side effects included 28 RCTs. Most of the RCTs were at high risk of bias mainly because of allocation concealment concerns. Reported oral side effects including oral soreness, gastric reflux or vomiting, and mouth or throat irritation.

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Vitamin B for the treatment of mouth ulcers

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This review of the efficacy of vitamin B in treating mouth ulcers included 16 RCTs published since 2010. All the included studies were published in Chinese with the findings that treatment was more effective in patients treated with vitamin B.

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Recurrent aphthous stomatitis and serum zinc levels

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This review of the potential association between zinc levels and occurrence of Recurrent aphthous stomatitis (RAS) included 19 case-controlled studies. The findings show a sigificant association between low zinc levels and RAS.

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Systemic Lupus Erythematosus: What are the orofacial manifestations and dental considerations?

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Marianne Dobson takes a look at this systematic review of the orofacial manifestations of systemic lupus erythematosus (SLE). The review included 30 studies and provides a narrative summary of a issues related to orofacial symptoms and management. However good quality prospective studies are needed to improve the the quality of evidence surrounding this topic.

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Vitamin D deficiency: Is it a risk factor for recurrent aphthous stomatitis?

Researchers in this study wanted to see if people with learning disabilities had higher levels of vitamin D deficiency than the general population

This review of a possible association between vitamin D deficiency and recurrent aphthous stomatitis (RAS) included 5 case control studies providing limited evidence that low levels of serum vitamin D might be a risk factor for RAS.

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Sodium lauryl sulphate (SLS): Does SLS-free toothpaste use benefit patients with recurrent aphthous stomatitis

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This review of the effects of sodium lauryl sulphate (SLS) free and SLS-containing toothpastes in patients with recurrent aphthous stomatitis (RAS) included 4 small RCTs with the findings suggesting that patients with RAS may benefit from using SLS-free toothpaste. However the quality of teh availabel studies is very low.

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Behçet’s disease: review found insufficient evidence to support or refute interventions for oral ulceration

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This review focuses on the treatment of oral ulceration in Behçet’s disease, 15 trials examining 13 different interventions were found. There was insufficient evidence to support or refute the use of any included intervention with regard to pain, episode duration, or episode frequency associated with oral ulcers, or safety of the interventions.

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