Epilepsy affects between 40-70 per 100,000 of the population in the developed world. Antiepileptic drugs (AEDs) in particular phenytoin (PHT) is associated with gingival hyperplasia(GH) . The aim of this review was to explore the effects of all AEDs on oral health. The authors searched PubMed, EMBASE the Cochrane library [read the full story...]
Medical treatment of systemic sclerosis (SSc), and its complications involves the use of immunosuppressants and calcium channel blockers which are known to increase the risk of developing gingival hyperplasia . In addition defective vascularity and alterations of the microcirculation of the gingival tissues may lead to gingival inflammation. Sicca symptoms [read the full story...]
Gingival overgrowth is an important adverse effect of phenytoin (PHT) therapy, occurring in about half of the patients. This study aimed to evaluate the effect of oral folic acid supplementation (0.5 mg/day) for the prevention of PHT-induced gingival overgrowth (PIGO) in children with epilepsy aged 6–15 years on PHT monotherapy [read the full story...]
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