Recurrent aphthous stomatitis – topical medications

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This review of different topical medications for the management of recurrent aphthous stomatitis (RAS) included 43 RCTs. No significant differences were found for any if the treatments assessed and a majority of the included RCTs (76%) were considered to be at high risk of bias.

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Recurrent aphthous stomatitis – topical interventions

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This review of the efficacy and safety of topical interventions used for recurrent aphthous stomatitis included 72 studies assessing 29 different interventions. Most of the interventions did not demonstrate significant differences with limitednumbers of studies for some interventions and overal limitations in the quality of the evidence.

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Burning mouth syndrome – topical interventions

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This review assessing the effectiveness of topical interventions in the management of burning mouth syndrome (BMS), based on the core outcome domains recommended by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) includes 8 RCTs and higlights the need to apply standardised outcome measures in future studies.

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Interventions for oral lichen planus

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This systematic review and network meta-analysis comparing interventions for the management of oral lichen planus included 55 RCTs. While the findings suggested that topical corticosteroids may be most effective the evidence is of low to very low certainty.

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Avulsed teeth: Storage media used before replantation

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This review of the effectiveness of any technique available to laypeople for storing an avulsed tooth compared with storage in milk or saliva included 33 studies. Findings suggest that milk, Hank’s balanced salt solution, propolis, oral rehydration salts, rice water, and cling film extend periodontal ligament cell viability before replantation.

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Direct pulp capping in primary teeth

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This review of direct pulp capping in vital primary teeth included 12 RCTs testing 16 different pulp capping agents. Interpretation of the available data is limited as few trials comparign the same agents and the quality of the trials is low.

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Anti-plaque agents in toothpaste: Are they helpful in managing gingivitis?

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This review of the efficacy of different anti-plaque chemical agents in managing gingivitis included 32 RCTS of toothpastes and 19 of mouthrinses suggested greater benefits with some agents.

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Aloe vera mouthwash: how does it compare with chlorhexidine?

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This review of the efficacy of aloe vera mouthrinse on plaque and gingival inflammation includes 6 RCTS providing very low quality evidence that aloe vera mouthwash is comparable to chlorhexidine in reducing gingival inflammation.

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Aloe vera for treatment of oral submucous fibrosis?

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This review effectiveness of aloe vera on alleviating the symptoms of oral submucous fibrosis included 6 RCTs . The findings suggest a possible benefit but 5 of the trials were at high risk of bias so the findings should be viewed cautiously.

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Tongue protector and topical aloe vera for treatment of burning mouth syndrome

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Burning mouth syndrome (BMS) presents as a subjective burning sensation of the tongue, lips or entire oral cavity, but does not manifest any objective lesions or laboratory test findings.  BMS is more common in middle-aged to elderly age groups. The aim of this study was to evaluate the efficacy of a tongue protector in combination [read the full story…]